By A. Gullo
Enhancing criteria of care is a true problem in in depth Care drugs. improving scientific functionality, sufferer safeguard, chance administration and audit represents the cornerstone for elevating the standard of care in ICU sufferers. communique is the platform from the place to begin to arrive a consensus in an exceptionally crowded sector, a special multidisciplinary and multiprofessional surroundings during which caliber of care and, finally, sufferer survival must be ameliorated.
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Extra resources for Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: Proceedings of the 22st Postgraduate Course in Critical Medicine Venice-Mestre, Italy - November 9-11, 2007
Even to research the technique demands a clear vision of why such a technique might be useful in a reasonably near future. In the case of microdialysis the vision is easy to understand: We want to detect pathological changes before we see them as clinical signs (Fig. 3). Ideally, we even want to detect those processes that eventually may lead to pathology. All of this comes down to the important fact that we need more time in order to successfully intervene. We need a window of opportunities. It seems reasonable to assume that tissue and organ pathology starts with changes in tissue biochemistry – even when the primary damage may be physical – as in traumatic brain injury (TBI).
The ratio is an absolute number, which can be used to compare one organ to another organ or one patient to another patient. In the brain we have rarely seen ratios above 25 in normal brain tissue and we therefore consider values above 25 as an indicator of the degree of ischaemia . Another valuable feature of the lactate/pyruvate ratio is that increases in lactate due to an increase in cell metabolism are not misinterpreted as a sign of ischaemia as long as the lactate/pyruvate ratio remains the same.
In this article I will give an overview of the different applications of clinical microdialysis. g. the application to the intestine, liver and heart. 30 U. Ungerstedt Markers of Tissue Biochemistry There is a fundamental difference between blood chemistry and tissue chemistry. In a blood sample we analyze chemicals that may originate from essentially every organ of the body – usually excluding the brain due to the blood brain barrier. e. chemical compounds that originate from a particular organ and have special relevance for the pathological state of that organ.
Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.: Proceedings of the 22st Postgraduate Course in Critical Medicine Venice-Mestre, Italy - November 9-11, 2007 by A. Gullo